Reason the Second: Diablo's Domain
While we're on the subject, guess what DiabloFans.com used to be called? Diablo3.com, until Blizzard acquired the domain name from the site's owner back in May. Website domain names are registered for plenty of reasons, though; it could be as simple as a company wanting the peace of mind of owning every possible aspect of their IP. We would have easily guessed Blizzard's intentions were simply cautionary, but the timing (and all the additional evidence surrounding it) makes us wonder if they don't have bigger intentions for the site after all. Every now and then a company has to register a domain name because they actually plan to use it, right?
Reason the Third: We Know a New Game Announcement is Coming
That is, at least, if Xfire is to be believed. Back on Friday the 13 (spooky!), DiabloII.com noticed a now-edited update on Xfire regarding the Invitational, which originally read in part, "follow the opening ceremony and discover what new game will be announced in our chat rooms together with hundreds of other Blizzard fans." Yes, new game (which happens to be the part of the announcement that was later redacted). Of course, that doesn't at all mean it's necessarily Diablo III, but again, added with all the other evidence, it sure is easy to read it that way.
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Resource: 1UP